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Updated: Sep 21, 2025

Microfluidic Mixers for Studying Protein Folding
Published on: April 10, 2012
ColabFold: making protein folding accessible to all
Milot Mirdita1, Konstantin Schütze2, Yoshitaka Moriwaki3,4
1Quantitative and Computational Biology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany. milot.mirdita@mpinat.mpg.de.
Abstract:
ColabFold offers accelerated prediction of protein structures and complexes by combining the fast homology search of MMseqs2 with AlphaFold2 or RoseTTAFold. ColabFold's 40-60-fold faster search and optimized model utilization enables prediction of close to 1,000 structures per day on a server with one graphics processing unit. Coupled with Google Colaboratory, ColabFold becomes a free and accessible platform for protein folding. ColabFold is open-source software available at https://github.com/sokrypton/ColabFold and its novel environmental databases are available at https://colabfold.mmseqs.com .
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