Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Motor Unit Stimulation01:20

Motor Unit Stimulation

When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative effects of low-level laser acupuncture and dry needling on clinical and functional outcomes in patients with chronic cervical myofascial pain syndrome: a randomized controlled trial.

Lasers in medical science·2026
Same author

A standardized, surgically relevant map of emergence for organ-specific branches in the human vagus nerve.

bioRxiv : the preprint server for biology·2026
Same author

Author Correction: Control of spatiotemporal activation of organ-specific fibers in the swine vagus nerve by intermittent interferential current stimulation.

Nature communications·2026
Same author

Efficacy and Safety of Asenapine in Bipolar Disorder: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Psychopharmacology bulletin·2026
Same author

Clinical predictors of long-term atrial fibrillation recurrence post catheter ablation: an ITHACA-database analysis.

The Journal of invasive cardiology·2026
Same author

Primary Intracranial DICER-1 Mutant Sarcoma: A Systematic Review of Existing Literature from 2000 to 2024.

Pakistan journal of medical sciences·2026

Related Experiment Video

Updated: Jul 24, 2026

Vagus Nerve Stimulation as a Tool to Induce Plasticity in Pathways Relevant for Extinction Learning
11:02

Vagus Nerve Stimulation as a Tool to Induce Plasticity in Pathways Relevant for Extinction Learning

Published on: August 21, 2015

23.7K

Strategies for precision vagus neuromodulation.

Umair Ahmed1, Yao-Chuan Chang1, Stefanos Zafeiropoulos1

  • 1Institute of Bioelectronic Medicine, Feinstein Institutes for Medical Research, Manhasset, New York, USA.

Bioelectronic Medicine
|May 31, 2022
PubMed
Summary

Precision vagus nerve stimulation offers a targeted therapy for autonomic disorders. This approach aims to improve treatment efficacy by modulating specific nerve fibers or branches, minimizing side effects.

Keywords:
Bioelectronic medicineBranchesFasciclesNeuromodulationNoninvasiveSelective vagus nerve stimulationUltrasoundVagus fibers

More Related Videos

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
04:29

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

Published on: January 7, 2019

28.9K
Laboratory Administration of Transcutaneous Auricular Vagus Nerve Stimulation taVNS: Technique, Targeting, and Considerations
06:31

Laboratory Administration of Transcutaneous Auricular Vagus Nerve Stimulation taVNS: Technique, Targeting, and Considerations

Published on: January 7, 2019

39.6K

Related Experiment Videos

Last Updated: Jul 24, 2026

Vagus Nerve Stimulation as a Tool to Induce Plasticity in Pathways Relevant for Extinction Learning
11:02

Vagus Nerve Stimulation as a Tool to Induce Plasticity in Pathways Relevant for Extinction Learning

Published on: August 21, 2015

23.7K
Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
04:29

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

Published on: January 7, 2019

28.9K
Laboratory Administration of Transcutaneous Auricular Vagus Nerve Stimulation taVNS: Technique, Targeting, and Considerations
06:31

Laboratory Administration of Transcutaneous Auricular Vagus Nerve Stimulation taVNS: Technique, Targeting, and Considerations

Published on: January 7, 2019

39.6K

Area of Science:

  • Neuroscience
  • Bioelectronic Medicine
  • Autonomic Physiology

Background:

  • The vagus nerve is crucial for autonomic regulation of bodily functions.
  • Vagus nerve stimulation (VNS) shows therapeutic potential for various disorders.
  • Current VNS lacks precision, potentially affecting non-targeted organs.

Purpose of the Study:

  • To review the anatomical and physiological basis for precision VNS.
  • To discuss strategies for targeted vagus neuromodulation.
  • To explore applications in neurological, cardiovascular, and gastrointestinal disorders.

Main Methods:

  • Review of anatomical and physiological literature on vagus nerve innervation.
  • Analysis of existing and proposed precision neuromodulation techniques.
  • Synthesis of therapeutic targets and potential strategies for specific conditions.

Main Results:

  • Vagus nerve anatomy supports precision modulation at fiber, fascicle, and branch levels.
  • Strategies include selective nerve stimulation and end-organ terminal modulation.
  • Precision VNS can target specific organs while sparing others.

Conclusions:

  • Precision neuromodulation of the vagus nerve is feasible and offers improved therapeutic potential.
  • Targeted VNS strategies can enhance efficacy and safety for autonomic disorders.
  • Further research into precision VNS is warranted for clinical translation.