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COVID-19 Presenting as a Seizure: A Kenyan Case Report
Syed Moosa Raza1, Farah Ebrahim2, Herman Ekea3
1Medicine, University of Central Florida, Orlando, USA.
Cureus
|May 31, 2022
Summary
This study reports the first case in sub-Saharan Africa of a COVID-19 patient experiencing seizures and confusion. It emphasizes considering coronavirus disease (COVID-19) in seizure differential diagnoses.
Area of Science:
- Neurology
- Infectious Diseases
Background:
- The novel coronavirus (COVID-19) pandemic has led to diverse clinical manifestations.
- Neurological complications, including epileptic seizures, are increasingly recognized but their etiologies remain unclear.
- COVID-19 infection can trigger pro-inflammatory cytokines, potentially causing neurotransmitter imbalance and neuronal hyperexcitability.
Observation:
- A COVID-19 positive patient presented with a seizure followed by confusion.
- This represents the first documented case of such a presentation in sub-Saharan Africa.
Findings:
- COVID-19 infection can manifest with neurological symptoms like seizures.
- The underlying mechanism may involve cytokine-induced neuronal dysfunction.
Implications:
- Clinicians should include COVID-19 in the differential diagnosis for patients presenting with new-onset seizures.
- This case underscores the broad neurological impact of SARS-CoV-2.
- Further research is needed to understand the link between COVID-19 and epilepsy.
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