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White-centered retinal hemorrhage revealing acute leukemia: A case report
Nadia Ben Abdesslem1,2, Nesrine Zaafrane1,2, Atf Ben Abderazek1,2
1Department of Ophthalmology, Farhat Hached University Hospital, Sousse, Tunisia.
Retinal hemorrhages, especially white-centered ones, can be an early sign of acute myeloid leukemia. Prompt ophthalmological examination is crucial for early diagnosis when these signs appear.
Area of Science:
- Ophthalmology
- Hematology
- Oncology
Background:
- Retinal manifestations are recognized as an early indicator of acute leukemia.
- White-centered hemorrhages (Roth spots) are common ocular findings in leukemia.
Observation:
- A 34-year-old man with no prior medical history presented with decreased visual acuity and fatigue.
- Ophthalmological examination revealed bilateral white-centered hemorrhages.
Findings:
- The patient was diagnosed with acute myeloid leukemia.
- The presence of Roth spots indicated a significant underlying hematological malignancy.
Implications:
- This case highlights the importance of fundus examination in patients presenting with unexplained visual changes.
- Early detection of retinal signs can lead to timely diagnosis and treatment of acute leukemia.
- A comprehensive etiological investigation is warranted upon identifying Roth spots.
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