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Updated: Sep 21, 2025

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Superior mesenteric venous thrombosis in a 47 years old male with protein S deficiency: A case report
Ayush Mohan Bhattarai1, Ashish Mohan Bhattarai2, Abinash Karki3
1Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal.
Introduction:
Mesenteric venous thrombosis is due to blood clot in veins that drain blood from the intestine. It may lead to mesenteric ischemia. Protein S deficiency is one of the causes of superior mesenteric vein thrombosis.
Case Presentation:
A 47 years old male patient presented with pain in the abdomen. Contrast CECT shows filling defect in the superior mesenteric venous thrombosis. Coagulometer showed lower protein S activity than that of normal.
Clinical Discussion:
Proper diagnosis is needed for early detection so that proper intervention can be made on time. Anticoagulation and vitamin K antagonists are given.
Conclusions:
Though rare, protein S deficiency should be considered a possible cause of mesenteric venous thrombosis.

