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Mesenteric venous thrombosis--1911 to 1984

R A Abdu, B J Zakhour, D J Dallis

    Surgery
    |April 1, 1987
    PubMed

    Insights

    Mesenteric venous thrombosis (MVT) often affects older adults with other illnesses. Early diagnosis and surgical intervention with anticoagulants can improve outcomes for MVT patients.

    Area of Science:

    • Gastroenterology
    • Vascular Surgery
    • Internal Medicine

    Background:

    • Mesenteric venous thrombosis (MVT) is a rare but serious condition affecting the blood supply to the intestines.
    • Understanding MVT's risk factors, presentation, and management is crucial for improving patient outcomes.

    Purpose of the Study:

    • To identify patient profiles at risk for developing mesenteric venous thrombosis (MVT).
    • To review the pathophysiology, clinical manifestations, diagnostic methods, and outcomes associated with MVT.

    Main Methods:

    • A comprehensive literature review was conducted, analyzing data from 372 patients with MVT (1911-1984).
    • Autopsy data from 99 patients were excluded from the primary analysis.

    Main Results:

    • MVT predominantly affects individuals in their sixth and seventh decades, with 81% having co-existing illnesses.
    • Abdominal pain disproportionate to physical findings, marked leukocytosis, and dehydration are suggestive of MVT.
    • Serosanguineous fluid from peritoneal tap is a valuable diagnostic indicator.

    Conclusions:

    • A high index of suspicion, coupled with early diagnosis and prompt surgical intervention, is key for MVT management.
    • The addition of anticoagulants alongside surgical treatment appears to enhance survival and reduce recurrence rates for MVT.

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