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Normative globe position values on orbital computed tomography in Australians.

Khizar Rana1, Valerie Juniat1, Wen Yong2

  • 1Department of Ophthalmology and Visual Sciences, University of Adelaide, Adelaide, Australia; South Australian Institute of Ophthalmology, Royal Adelaide Hospital, Adelaide, Australia.

Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie
|May 31, 2022
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Summary

This study establishes normal computed tomography measurements for globe position, interzygomatic distance (IZD), and globe dimensions in an Australian population. These normative data aid in diagnosing conditions like exophthalmos and enophthalmos.

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Area of Science:

  • Ophthalmology
  • Radiology
  • Medical Imaging

Background:

  • Accurate assessment of orbital anatomy is crucial for diagnosing conditions affecting globe position.
  • Establishing normative data for globe position and dimensions is essential for clinical interpretation of orbital imaging.
  • Computed tomography (CT) provides detailed anatomical information of the orbit.

Purpose of the Study:

  • To determine normal globe position values, interzygomatic distance (IZD), and globe axial length and width using computed tomography (CT) in an Australian cohort.
  • To provide reference values for radiologic assessment of orbital structures.
  • To establish normative data for diagnosing radiologic exophthalmos or enophthalmos.

Main Methods:

  • A retrospective cohort study design was employed.
  • Patients undergoing CT of the orbits were included, with exclusions for bilateral disease, prior orbital surgery, or poor scan quality.
  • Globe position measurements (anterior and posterior globe position relative to the interzygomatic line) and globe dimensions (axial length and width) were obtained from axial CT slices through the midglobe.

Main Results:

  • Normal measurements (mean ± SD) were: IZD, 97.4 ± 4.1 mm; anterior globe position, 18.8 ± 2.8 mm; posterior globe position, 6.2 ± 2.9 mm; axial globe length, 24.9 ± 1.1 mm; and axial globe width, 25.9 ± 1.2 mm.
  • Significant positive correlations were observed between IZD and anterior globe position (r=0.15, p=0.03), axial globe length (r=0.33, p<0.01), and axial globe width (r=0.30, p<0.01).

Conclusions:

  • The study provides normative computed tomography measurements for globe position, IZD, and globe dimensions in an Australian cohort.
  • These established normative data can be utilized for the diagnosis of radiologic exophthalmos or enophthalmos.
  • This research contributes valuable reference values for orbital imaging interpretation in clinical practice.