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Published on: March 17, 2023
Application value of fluorescence visualization-assisted technology in the resection of liver cancer: A systematic
Qian Xue1, Jianping Wu1, Zehua Lei1
1Department of Hepatopancreatobiliary Surgery, People's Hospital of Leshan, Leshan, Sichuan 614000, China.
Background:
The purpose of this study is to systematically evaluate the application value of fluorescence visualization-assisted technology in the resection of liver cancer.
Methods:
A systematic search was conducted of the literature on fluorescence visualization-assisted technology in the resection of liver cancer in randomized controlled trials, semi-randomized controlled trials, and observational studies. The retrieval period was up to April 2022. Publications and conference papers in English were manually searched and the references included in the literature were traced. After evaluating the quality of the included studies, the total analysis and subgroup analysis based on pathological types of liver malignant lesions were conducted using the Review Manager 5.1 software.
Results:
Eight studies were included with a total of 646 patients enrolled. Analysis indicated that the fluorescence visualization could significantly shorten the operative time [mean difference (MD) = -38.33; 95% CI = -71.70 ∼ -4.96; P = 0.02], reduce blood loss [MD = 12.96; 95% CI = 11.98 ∼ 13.95; P < 0.001], shorten the hospital stay [MD = -8.0; 95% CI = -14.29 ∼ -1.72; P = 0.01], reduce postoperative complications [odds ratio (OR) = 0.44, 95% CI = 0.21 ∼ 0.91; P = 0.03], and reduce the recurrence rate [OR = 0.41, 95% CI = 0.21 ∼ 0.77; P = 0.006].
Conclusion:
This systematic review revealed the superiority of fluorescence visualization-assisted technology for the resection of liver cancer, and offers high practical application value.
