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Is COVID-19 really a geriatric syndrome?

Mohammad Amin Akbarzadeh1, Mohammad-Salar Hosseini2

  • 1Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran; Research Center for Evidence-Based Medicine, Tabriz University of Medical Sciences, Tabriz, Iran; Iranian Evidence-Based Medicine (EBM) Centre, Joanna Briggs Institute Affiliated Group, Tabriz, Iran.

Ageing Research Reviews
|May 31, 2022
PubMed

Insights

Older adults show higher rates of COVID-19 vaccine hesitancy due to uncertainty and unwillingness. This hesitancy may impact vaccine uptake and increase mortality rates in this vulnerable population.

Area of Science:

  • Gerontology
  • Epidemiology
  • Public Health

Background:

  • Geriatric syndromes are common in older adults and associated with increased mortality.
  • COVID-19 disproportionately affects older individuals, with higher mortality rates.
  • Geriatric syndromes may exacerbate COVID-19 complications and outcomes.

Purpose of the Study:

  • To analyze the prevalence of COVID-19 vaccine unwillingness and uncertainty in older populations.
  • To evaluate the impact of vaccine hesitancy on vaccine uptake among the elderly.
  • To discuss the implications of vaccine hesitancy on COVID-19 mortality rates in older adults.

Main Methods:

  • Systematic review of existing studies.
  • Meta-analysis of pooled data on vaccine hesitancy in older adults.
  • Analysis of factors contributing to unwillingness and uncertainty regarding COVID-19 vaccination.

Main Results:

  • Significant prevalence of vaccine unwillingness and uncertainty identified in older adults.
  • Vaccine hesitancy is linked to lower vaccine uptake rates in this demographic.
  • The findings highlight a critical public health challenge in achieving high vaccination coverage among the elderly.

Conclusions:

  • Addressing vaccine hesitancy is crucial for protecting older adults from severe COVID-19 outcomes.
  • Targeted interventions are needed to overcome barriers to COVID-19 vaccination in the geriatric population.
  • Reducing uncertainty and unwillingness can improve vaccine uptake and mitigate mortality risks.

Keywords:
COVID-19Geriatric syndromeImmunosenescenceOlder adultsVaccination

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