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Updated: Sep 21, 2025

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
An incidental finding behind adrenal incidentaloma.
Filippo Crimì1,2, Giulio Barbiero2, Irene Tizianel1,3
1Department of Medicine DIMED, University of Padova, Padova, Italy.
A rare case highlights that acute pancreatitis complications can mimic adrenal masses. Imaging can be misleading, but advanced MRI and multidisciplinary review correctly diagnosed a necrotic collection, not adrenal cancer.
Area of Science:
- Endocrinology
- Gastroenterology
- Radiology
Background:
- Adrenal incidentalomas can present with complex imaging features.
- Necrotic collections from pancreatitis may mimic adrenal masses on initial imaging.
- Differentiating these lesions is crucial for appropriate patient management.
Purpose of the Study:
- To report a case where a necrotic collection post-pancreatitis mimicked an adrenal mass.
- To emphasize the role of advanced imaging and multidisciplinary discussion in diagnosis.
- To highlight potential diagnostic challenges in adrenal imaging.
Main Methods:
- Case presentation of a 61-year-old male with abdominal pain and a suspected adrenal lesion.
- Utilized abdominal ultrasonography, contrast-enhanced CT, MRI, and PET/CT for lesion characterization.
- Performed CT-guided drainage and fluid analysis for definitive diagnosis.
Main Results:
- Initial imaging suggested an adrenocortical tumor, but hormonal evaluation was normal.
- MRI revealed inhomogeneous fluid collection with peripheral enhancement, and PET/CT showed minimal uptake.
- CT-guided drainage confirmed an acute necrotic collection secondary to focal pancreatitis.
Conclusions:
- Acute necrotic collections after pancreatitis can mimic adrenal masses, posing a diagnostic challenge.
- MRI offers superior characterization of complex adrenal lesions compared to CT.
- A multidisciplinary approach is essential for managing adrenal incidentalomas with equivocal imaging findings.
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