Related Experiment Video
Updated: Sep 21, 2025

Experimental Screening Protocols, Immunocytochemistry and Microscopy-based Imaging Techniques for Penium margaritaceum
Published on: March 28, 2025
Two New Alkaloids from the Marine-Derived Fungus Penicillium sp. LSH-3-1
Sihui Li1, Yihan Ma1, Lixia Wang2
1Ocean College, Zhejiang University, Zhoushan, 316021, P. R. China.
Abstract:
Two new alkaloids, peniokaramine (1) and penipyranopyridine (6), along with seven known compounds, were isolated from the marine-derived fungus Penicillium sp. LSH-3-1. Their structures were elucidated from UV, IR, MS, 1D and 2D NMR spectroscopic data. The anti-inflammatory potential of compounds 1-8 in LPS-induced RAW264.7 cells was detected, revealing that compounds 3 and 5 significantly decreased LPS-induced production of pro-inflammatory mediators, including NO, IL-6 and TNF-α. Compounds 1-8 were also screened for their cytotoxic activity against A549 cells and compound 1 showed moderate activity.
More Related Videos
10:57Scanning Electron Microscopy SEM Protocols for Problematic Plant, Oomycete, and Fungal Samples
Published on: February 3, 2017
12:02An Efficient Method for the Synthesis of Peptoids with Mixed Lysine-type/Arginine-type Monomers and Evaluation of Their Anti-leishmanial Activity
Published on: November 2, 2016
Related Concept Videos
Red Algae
Green Algae