Hospitalization and comorbidity in children with type 2 diabetes
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Updated: Sep 21, 2025

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
Elizabeth A C Sellers1,2, Lorraine McLeod3, Heather J Prior4
1Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada.
Insights
Children with type 2 diabetes (T2D) face higher hospitalization rates than matched controls and those with type 1 diabetes (T1D). Mental illness is a leading cause for T2D hospital admissions.
Area of Science:
- Pediatric Endocrinology
- Public Health
- Healthcare Management
Background:
- Type 2 diabetes (T2D) is increasingly diagnosed in children, necessitating an understanding of associated healthcare utilization.
- Hospitalization patterns in pediatric T2D are not well-characterized, impacting resource allocation and care planning.
Purpose of the Study:
- To quantify hospitalization rates and identify primary reasons for admission in children with T2D.
- To compare these hospitalization metrics against a matched cohort without diabetes and a cohort with type 1 diabetes (T1D).
Main Methods:
- Utilized population-based cohorts of children aged 7-18 years with prevalent T2D, matched controls, and T1D.
- Linked clinical registry data with health records to analyze hospitalizations using ICD-9CM and ICD-10CA codes.
Main Results:
- Children with T2D exhibited significantly higher hospitalization rates compared to matched controls and T1D cohorts across pre-diagnosis, first-year post-diagnosis, and five-year post-diagnosis periods.
- Mental illness emerged as the most frequent reason for hospital admission among children with T2D and control groups.
- In contrast, endocrine-related causes were the primary drivers of hospitalization in children with T1D.
Conclusions:
- The findings highlight elevated hospitalization risks for children with T2D, underscoring the need for targeted healthcare interventions.
- Understanding these distinct hospitalization patterns is crucial for informing health policy and optimizing care strategies for pediatric T2D.
- This research provides essential data for managing the growing population of children diagnosed with T2D.
Objective:
To describe hospitalization rates and reasons for hospitalization in children with type 2 diabetes (T2D) and to compare these rates to a matched cohort without diabetes and to children with type 1 diabetes (T1D).
Methods:
Population-based cohorts of 528 children (7-18 years of age) with prevalent T2D, 1519 matched control children without diabetes and 778 children with T1D were identified from a clinical registry and linked to health care records to assess hospitalizations and reasons for hospitalizations using ICD-9CM and ICD-10CA codes.
Results:
Children with T2D are more likely than their matched controls and children with T1D to be admitted to hospital in the year prior to diagnosis {RR 2.83 (1.77, 4.53) p < 0.0001 and 8.05 (4.05, 16.00) p < 0.0001, respectively}, in the first year post diagnosis {RR 3.19 (2.08, 4.89) p < 0.0001 and 3.04 (1.86, 4.98) p < 0.0001, respectively} and in the 5 year post diagnosis period {RR 1.99 (1.56, 2.53) p < 0.0001 and 1.91 (1.48, 2.46) p < 0.0001, respectively}. Mental illness was the most common cause for hospital admission in both children with T2D and their matched controls.
Conclusions:
This differs from children with T1D where endocrine causes constitute the most common reason for hospital admission. This analysis provides novel data on hospitalization rates and diagnoses in the increasing population of children with T2D. This information is important to inform health care programming and health policy planning to best meet the needs of this population.
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