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Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
[Value of three-dimensional speckle-tracking imaging in evaluating left ventricular systolic function and its
Li Zhou1, Shu-Xia Wang1, Fang Wang1
1Department of Cardiac Functions Examination, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
Insights
Children with obesity show altered left ventricular systolic function and peripheral arterial elasticity. Global longitudinal strain (GLS) in obese children correlates with brachial-ankle pulse wave velocity (baPWV), indicating a link between heart function and arterial stiffness.
Area of Science:
- Cardiology
- Pediatrics
- Medical Imaging
Background:
- Childhood obesity is a growing concern with potential cardiovascular implications.
- Assessing left ventricular systolic function and peripheral arterial elasticity is crucial for early detection of cardiovascular risks in obese children.
Purpose of the Study:
- To evaluate left ventricular systolic function using three-dimensional speckle-tracking imaging (3D-STI) in children with simple obesity.
- To investigate the correlation between cardiac function parameters and peripheral arterial elasticity measures in this population.
Main Methods:
- Three-dimensional speckle-tracking imaging (3D-STI) was employed to measure global longitudinal strain (GLS), global radial strain (GRS), and global circumferential strain (GCS) in children.
- Peripheral arterial elasticity was assessed using ankle-brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV).
- Participants were categorized into obesity, overweight, and normal weight groups for comparative analysis.
Main Results:
- While GLS, GRS, and GCS showed no significant difference between obese and normal groups, the overweight group exhibited significantly higher GLS.
- Obesity and overweight groups displayed significantly lower ABI and higher baPWV compared to the normal group, indicating reduced arterial elasticity.
- In obese children, GLS positively correlated with baPWV, suggesting a relationship between systolic function and arterial stiffness.
Conclusions:
- Children with simple obesity exhibit alterations in both left ventricular systolic function and peripheral arterial elasticity.
- A significant correlation exists between specific measures of cardiac function (GLS) and arterial stiffness (baPWV) in obese children.
Objectives:
To study the application of three-dimensional speckle-tracking imaging in evaluating left ventricular systolic function and its correlation with peripheral arterial elasticity in children with simple obesity.
Methods:
Random sampling combined with convenience sampling was used to obtain research samples, and then the samples were divided into an obesity group (23 cases), an overweight group (21 cases), and a normal group (24 cases). Three-dimensional speckle-tracking imaging was used to measure the global longitudinal strain (GLS), global radial strain (GRS), and global circumferential strain (GCS) of the left ventricle. An automatic arteriosclerosis tester was used to measure ankle-brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV). These parameters were compared among the three groups. The correlation of three-dimensional speckle-tracking parameters with ABI and baPWV was evaluated.
Results:
There were no significant differences in GLS, GRS, and GCS between the obesity and normal groups (P>0.05). The overweight group had a significantly higher GLS than the normal group [(-24±7) vs (-19±12), P<0.05]. The obesity and overweight groups had a significantly lower ABI than the normal group [(1.00±0.09)/(1.09±0.13) vs (2.25±0.13), P<0.05). The obesity group had a significantly higher baPWV than the normal group [(978±109) vs (905±22), P<0.05]. In the children with obesity, GLS was positively correlated with baPWV (r=0.516, P<0.05) , but not correlated with ABI (P>0.05), and GCS and GRS had no significant correlation with ABI or baPWV (P>0.05).
Conclusions:
There are varying degrees of changes in left ventricular systolic function and peripheral arterial elasticity in children with simple obesity, and there is a certain correlation between them.
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