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Quality Improvement to Engage General Pediatrics in Reducing Inaccurate Penicillin Allergy Labels
Douglas J McLaughlin1, Mitchell Grayson2, Christina Toth3
1Division of Primary Care Pediatrics Nationwide Children's Hospital and The Ohio State University School of Medicine (DJ McLaughlin), Columbus, Ohio.
Insights
Pediatric clinics can safely remove inaccurate penicillin allergy labels through education and oral amoxicillin challenges. This quality improvement project reduced the overall proportion of patients with these labels, decreasing unnecessary referrals.
Area of Science:
- Clinical Medicine
- Pediatrics
- Allergy and Immunology
Background:
- Inaccurate penicillin allergy labels are common in pediatric populations.
- These labels can lead to the use of alternative, potentially less effective or more toxic antibiotics.
- Over-labeling contributes to unnecessary referrals to allergy specialists.
Purpose of the Study:
- To decrease the proportion of patients with inaccurate penicillin allergy labels in a general pediatric clinic.
- To implement and evaluate interventions aimed at label removal.
- To assess the impact on allergy referral rates and label removal during clinic visits.
Main Methods:
- A collaborative quality improvement project was conducted from October 2017 to December 2021.
- Interventions included education, feedback, EHR alerts, and oral amoxicillin challenges.
- Control charts monitored referral rates, label removal, and the overall proportion of penicillin-allergic patients.
Main Results:
- Referral rates to allergy clinic increased significantly from 1.9% to 20.4%.
- In-clinic label removal increased from 1.1% to 6.6% for labeled patients.
- The overall proportion of penicillin allergy-labeled patients decreased from 3.4% to 2.2%.
Conclusions:
- General pediatric practitioners can effectively remove inaccurate penicillin allergy labels with proper education and collaboration.
- Pediatricians can manage low-risk evaluations, reducing the burden on allergists.
- This approach allows specialists to focus on higher-risk patients.
Objective:
To remove inaccurate penicillin allergy labels in the general pediatric clinic setting.
Methods:
From October 2017 through December 2021, this collaborative, quality improvement project used education, feedback, electronic health record alerts, and the introduction of oral amoxicillin challenges in a general pediatric clinic setting with the primary aim of decreasing the proportion of penicillin allergy labeled patients. Control charts were used to track the relationship between interventions and improvements in referral rates to allergy clinic, removal of the allergy label at clinic visits and the overall proportion of clinic patients labeled as PCN allergic.
Results:
Referral rates to allergy clinic for penicillin allergy labeled patients increased from a baseline mean of 1.9% to 20.4%. The proportion of PCN allergy labeled patients who had the label removed during a pediatric clinic visit increased from a baseline of 1.1% to 6.6%. The overall proportion of penicillin allergy labeled clinic patients decreased from a baseline of 3.4% to 2.2%.
Conclusion:
With adequate education and collaboration with allergists, general pediatric practitioners can play a significant role in removing inaccurate penicillin allergy labels. Pediatricians can remove some of the burden placed on allergists by evaluating low risk patients in the primary care setting while referring higher risk patients to the specialist.
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