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Updated: Sep 21, 2025

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
Published on: May 6, 2022
[Advances in analytical methods of relationship between exposome and health outcomes]
1Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University/Ministery of Education Key Laboratory of Population Health Across Life Cycle, Hefei 230032, China.
Abstract:
The research on the relationship between single exposure and health outcomes is not comprehensive without a capability of systematically revealing the cause. At present, some studies have explored the relationship between exposome and health outcomes. However, due to the large data of exposome and the correlation among exposure factors, there is still a lack of effective methods to analyze the relationship between exposome and health outcomes. This study reviews the previous literature, combs the analysis methods of the relationship between exposome and health outcomes, and points out that agnosticism combined with middle-level information can significantly reduce the false positive rate, so as to provide a reference for accurately identifying the influencing factors of health outcomes in extensive exposome.
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