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Neurological disorders and small bowel dysmotility
Nikolaos Kamperidis1, Jeremy Nightingale
1St Mark's Hospital, Harrow, London, UK.
Current Opinion in Gastroenterology
|June 1, 2022
Summary
Small bowel dysmotility is common in neurological disorders, impacting quality of life and outcomes. Addressing enteric dysmotility is crucial for managing symptoms and preventing malnutrition in these patients.
Area of Science:
- Gastroenterology
- Neurology
- Internal Medicine
Background:
- Small bowel dysmotility is frequently observed in patients with neurological disorders.
- Failure to recognize and manage this condition can negatively affect patient well-being and neurological prognosis.
- Up to two-thirds of neurological patients may present with symptoms related to small bowel dysmotility.
Purpose of the Study:
- To elucidate the mechanisms and consequences of enteric dysmotility in neurological conditions.
- To outline current and potential treatment strategies for small bowel dysmotility in this population.
Main Methods:
- This review synthesizes existing literature on small bowel dysmotility in neurological disorders.
- It examines the pathophysiology, clinical manifestations, and therapeutic interventions.
Main Results:
- Enteric dysmotility arises from central and peripheral nervous system disorders or generalized muscle conditions.
- Symptoms include abdominal pain, nausea, vomiting, bloating, constipation, or diarrhea, often leading to malnutrition.
- Dysmotility impairs nutrient and medication absorption, affecting social and professional functioning.
Conclusions:
- Small bowel dysmotility is a significant complication in neurological patients, requiring careful management.
- Addressing symptoms and preventing malnutrition are paramount for improving patient outcomes.
- Further research into targeted therapies for enteric dysmotility in neurological disorders is warranted.
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