Related Experiment Video
Updated: Sep 21, 2025

08:20
Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
6.5K
Assessment of Bacterial Load Using 3.8% SDF as an Irrigant in Pulpectomized Primary Molars: A Randomized Controlled
Viral Maru1, Dimple Padawe1, Shilpa Naik2
1Department of Pediatric Dentistry, Government Dental College and Hospital, Mumbai, Maharashtra, India.
Summary
This study found that 3.8% silver diamine fluoride (SDF) significantly reduced bacterial load in primary molars during pulpectomy. SDF proved more effective than sodium hypochlorite (NaOCl) in reducing bacteria.
Area of Science:
- Endodontics
- Pediatric Dentistry
- Microbiology
Background:
- Pulpectomy is a common procedure for primary molars with pulp necrosis.
- Effective bacterial reduction is crucial for successful pulpectomy outcomes.
- Alternative irrigating solutions are being explored to enhance disinfection protocols.
Purpose of the Study:
- To evaluate the efficacy of 3.8% silver diamine fluoride (SDF) as an irrigating solution for reducing bacterial load in pulpectomized primary molars.
- To compare the antibacterial effectiveness of 3.8% SDF with 1% sodium hypochlorite (NaOCl).
Main Methods:
- A randomized controlled clinical trial involved 60 primary molars with pulp necrosis.
- Thirty canals were irrigated with 3.8% SDF and 30 with 1% NaOCl.
- Microbiological samples were collected before and after irrigation, analyzed using the Agar plate method.
Main Results:
- Both 3.8% SDF and 1% NaOCl significantly reduced bacterial load (p < 0.001).
- Post-irrigation, 3.8% SDF demonstrated a statistically significant greater reduction in bacterial load compared to 1% NaOCl.
- Agar plate method confirmed significant bacterial reduction in both groups.
Conclusions:
- 3.8% SDF is an effective irrigant for reducing bacterial load in pulpectomized primary molars.
- 3.8% SDF can be considered a viable alternative irrigant to NaOCl in pediatric endodontics.
- Further research may explore optimal concentrations and protocols for SDF in pulpectomy.

