Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Improving Translational Accuracy02:07

Improving Translational Accuracy

11.9K
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
11.9K
Case Studies01:22

Case Studies

12.2K
There are many research methods available to psychologists in their efforts to understand, describe, and explain behavior and the cognitive and biological processes that underlie it.
12.2K
Parallel Processing01:20

Parallel Processing

254
The brain processes sensory information rapidly due to parallel processing, which involves sending data across multiple neural pathways at the same time. This method allows the brain to manage various sensory qualities, such as shapes, colors, movements, and locations, all concurrently. For instance, when observing a forest landscape, the brain simultaneously processes the movement of leaves, the shapes of trees, the depth between them, and the various shades of green. This enables a quick and...
254

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

FAIR in practice: minimum metadata schema for bioinformatics analytics by machines.

Journal of biomedical semantics·2026
Same author

[Training conditions in postgraduate family medicine training in Bavaria and the role of the Competence Center: A comparative cross-sectional study].

Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen·2026
Same author

Work-life integration in interprofessional general practice collaboration: a qualitative exploration of different trends among Bavarian general practitioners.

BMJ open·2026
Same author

The medical competency training "climate-sensitive health counseling" - an interdisciplinary approach in planetary health education.

GMS journal for medical education·2026
Same author

[Gender differences in the willingness to transition to interprofessional general practice teams].

Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))·2026
Same author

KGAP: An RDF knowledge graph of agricultural commodity prices.

Data in brief·2026
Same journal

Inner layer security reinforcement for instant payment systems: a dual layer encryption-steganography evaluation in Brunei's digital payment context.

Frontiers in big data·2026
Same journal

Measuring the impact of virtualization and containerization on the environment when using GPUs for processing the AI models.

Frontiers in big data·2026
Same journal

Using artificial intelligence to improve governance and public services in Africa.

Frontiers in big data·2026
Same journal

Case count metric for comparative analysis of entity resolution results.

Frontiers in big data·2026
Same journal

Data field theory: a geometric framework for learning on Riemannian manifolds with synthetic validation and limitation analysis.

Frontiers in big data·2026
Same journal

Correction: Explainable gradient convolutional vector fuzzy pattern analysis based on ensemble model for facial expression recognition.

Frontiers in big data·2026
See all related articles

Related Experiment Video

Updated: Sep 21, 2025

Author Spotlight: Alignment of Synchronized Time-Series Data Using the Characterizing Loss of Cell Cycle Synchrony Model for Cross-Experiment Comparisons
07:59

Author Spotlight: Alignment of Synchronized Time-Series Data Using the Characterizing Loss of Cell Cycle Synchrony Model for Cross-Experiment Comparisons

Published on: June 9, 2023

1.5K

FAIR Digital Twins for Data-Intensive Research.

Erik Schultes1,2, Marco Roos1,3, Luiz Olavo Bonino da Silva Santos4

  • 1Leiden Institute for FAIR and Equitable Science, Leiden, Netherlands.

Frontiers in Big Data
|June 1, 2022
PubMed
Summary
This summary is machine-generated.

This study introduces the FAIR Digital Twin (FDT), a universally machine-actionable concept. It proposes an architecture for composing, storing, and reusing FDTs for data-intensive research within open science frameworks.

Keywords:
FAIR Digital ObjectFAIR Digital TwinFAIR guiding principlesKnowletaugmented reasoningdata stewardshipmachine learningnanopublications

More Related Videos

Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering
09:43

Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering

Published on: November 22, 2019

6.4K
Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine
08:53

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Published on: January 26, 2024

1.2K

Related Experiment Videos

Last Updated: Sep 21, 2025

Author Spotlight: Alignment of Synchronized Time-Series Data Using the Characterizing Loss of Cell Cycle Synchrony Model for Cross-Experiment Comparisons
07:59

Author Spotlight: Alignment of Synchronized Time-Series Data Using the Characterizing Loss of Cell Cycle Synchrony Model for Cross-Experiment Comparisons

Published on: June 9, 2023

1.5K
Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering
09:43

Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering

Published on: November 22, 2019

6.4K
Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine
08:53

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Published on: January 26, 2024

1.2K

Area of Science:

  • Digital Twin technology
  • Data science
  • Open science
  • Information science

Background:

  • Technical components for Digital Twins (DT) are available.
  • A conceptual gap exists in generalizing DTs to be FAIR (Findable, Accessible, Interoperable, Reusable) and machine-actionable.
  • Existing semantic artifacts can be leveraged for this generalization.

Purpose of the Study:

  • To conceptually clarify and analyze a generalized FAIR Digital Twin (FDT).
  • To propose a methodological overview and architectural design for FDTs.
  • To support data-intensive research using privacy-preserving, GDPR-compliant open science principles.

Main Methods:

  • Review of existing semantic artifacts.
  • Development of a higher-order data model for FDTs.
  • Proposal of an architectural design for FDT composition, storage, and reuse.

Main Results:

  • A conceptual framework for FAIR Digital Twins (FDTs) is presented.
  • An architectural design is proposed for creating, managing, and utilizing FDTs.
  • Emphasis is placed on privacy-by-design and GDPR compliance for open science.

Conclusions:

  • The FAIR Digital Twin (FDT) concept bridges the gap towards universally machine-actionable digital twins.
  • The proposed architecture facilitates the practical implementation of FDTs in data-intensive research.
  • This work supports the advancement of GDPR-compliant, privacy-preserving open science initiatives.