[Initial clinical experience using an interdisciplinary management concept for pregnant patients with liver damage]

Among 6,404 deliveries in 49 cases (0.8%) a liver disease was diagnosed in the course of pregnancy. The onset of the disease happened exclusively in the last trimester of pregnancy. In 36 pregnant women a hyperbilirubinaemia of diagnostic value was stated. As an informing diagnostic procedure the only determination of the alanine-aminotransferase activity has been proved to be sufficient. In every fifth pregnant woman the liver disease was observed in connection with a preeclampsia. The preterm delivery rate was 16.3%. An intrauterine growth retardation was found in 22.4% of women with hepatopathy during pregnancy. In 5 out of 34 patients asked for a post partum control a manifestation of the liver disease, respectively a cholecystopathia, was present and follow-ups were necessary. An interdisciplinary concept of treatment is emphasized to treat these pregnant women in cooperation with the specialist of internal medicine. Methodically an additional sheet of documentation is used, which contains important data of patients history and all obstetrical, clinical and laboratory results accompanying the pregnant woman during pregnancy and post partum controls.