[Changes in the hemostatic function of muscle tissue in phylogenesis]

Studies have been made on coagulating and fibrinolytic activity of muscle tissue from various animals (earthworm, clam, car, frog, pigeon, rat). It was shown that extracts from muscles of these animals contain activators and inhibitors of hemocoagulation and fibrinolysis, exhibiting also antiheparin activity. It is concluded that progressive development of hemostatic function of muscle tissue involves the decrease in anticoagulating activity and the increase of thromboplastic activity.