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Mucinous cystic liver neoplasm with invasive component and sarcomatous differentiation
Daniel Aparicio-López1, Ana Palomares-Cano1, Carlos Hörndler-Algarate2
1Department of Surgery, Miguel Servet University Hospital, Zaragoza, Spain.
Background:
Hepatobiliary mucinous cystic neoplasms (MCN) harbor an invasive carcinoma in 16% of the cases, mainly tubular type, but occasionally sarcomatoid or undifferentiated, these entities being frankly rare.
Methods:
We present the case of a liver MCN with an invasive component and sarcomatous degeneration.
Results:
The patient was treated surgically with subsequent adjuvant chemotherapy (capecitabine), presenting tumor progression after three months with peritoneal carcinomatosis and liver recurrence. The patient died due to liver failure 4 months after surgery.
Conclusion:
MCN with an invasive component and sarcomatous degeneration are very rare, present advanced stages, show aggressive behavior, and have a poor prognosis.
