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Transcriptome and Immunohistochemical Analyses in TBX4- and FGF10-Deficient Lungs Imply TMEM100 as a Mediator of

Justyna A Karolak1, Gail Deutsch2, Tomasz Gambin1,3

  • 1Baylor College of Medicine Houston, Texas.

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|June 1, 2022
PubMed
Abstract

No abstract available in PubMed .

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Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
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