Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Imaging Studies VII: Vascular Imaging

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Posterior hyaloid fibrosis in Toxoplasma chorioretinitis.

Eye (London, England)·2026

Same author

Degeneration of Interpericyte Tunneling Nanotubes Can Occur in the Absence of Pericyte Loss in Diabetic Retina Disease.

Investigative ophthalmology & visual science·2026

Same author

AI-Enabled Mapping of Structure-Hazard Relationships for Emerging Contaminants.

Environment & health (Washington, D.C.)·2026

Same author

Peripapillary pachychoroid syndrome: Clinical and imaging features, diagnostic differentiation and therapeutic strategies.

Survey of ophthalmology·2026

Same author

Predicting the progression of proliferative diabetic retinopathy: Pathophysiology, imaging phenotypes, and determinants of disease persistence despite therapy.

Survey of ophthalmology·2026

Same author

Pictilisib and nutrient stress synergize to induce methuosis via PI(4,5)P<sub>2</sub>-dependent macropinocytic dysregulation in cancer cells.

Cell death & disease·2026

Search research articles

Related Experiment Video

Updated: Sep 21, 2025

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Published on: February 18, 2022

Macular Vascular Imaging and Connectivity Analysis Using High-Resolution Optical Coherence Tomography.

Diogo Cabral^1,2, Ana C Fradinho², Telmo Pereira²

¹Vitreous Retina Macula Consultants of New York, NY, USA.

Translational Vision Science & Technology

|June 1, 2022

Summary

High-resolution OCT reveals a hybrid blood flow circuitry in the human macula. This study characterizes macular vascular connectivity, detailing inflow and outflow pathways in both superficial and deep vascular complexes.

More Related Videos

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Published on: January 10, 2019

Related Experiment Videos

Last Updated: Sep 21, 2025

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Published on: February 18, 2022

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Published on: January 10, 2019

Area of Science:

Ophthalmology
Medical Imaging
Vascular Biology

Background:

Understanding macular blood flow is crucial for diagnosing and treating retinal diseases.
Current imaging techniques have limitations in resolving complex vascular networks in vivo.
High-resolution optical coherence tomography (HighRes OCT) offers potential for detailed vascular visualization.

Purpose of the Study:

To characterize macular blood flow connectivity in vivo.
To utilize high-resolution optical coherence tomography (HighRes OCT) for detailed vascular analysis.
To investigate the interplay between superficial and deep vascular complexes in the macula.

Main Methods:

A cross-sectional, observational study involving healthy participants.
Dense perifoveal HighRes OCT raster scans were acquired.
Vascular segmentation and rendering were performed using specialized software, integrating flow and structural data.

Main Results:

Analysis of 422 inflow and 459 outflow connections in eight eyes.
Identified direct arteriolar connections to the superficial vascular complex (SVC) and intermediate capillary plexus (ICP).
Characterized deep capillary plexus (DCP) inflow and prevalent superficial draining venules, noting distinct DCP venule morphology.

Conclusions:

Macular blood flow exhibits a hybrid circuitry, integrating superficial and deep vascular networks.
HighRes OCT provides precise segmentation consistent with microscopy, confirming complex vascular patterns.
Findings enhance understanding of retinal vascular architecture and disease mechanisms.