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Updated: Sep 21, 2025

Three-dimensional Optical-resolution Photoacoustic Microscopy
Published on: May 3, 2011
Spectral interference contrast based non-contact photoacoustic microscopy realized by SDOCT
Abstract:
We introduce a method to extract the photoacoustic (PA) signal from a contrast reduction of the interference spectrum acquired by spectral domain optical coherence tomography (SDOCT). This all-optical detection is achieved in a noncontact manner directly on the water surface covered on the sample by using its specular reflection. During SDOCT exposure, the phase of the interference spectrum keeps shaking according to the water surface vibration induced by PA excitation. This results in an interference contrast reduction which is quantified by a fast Fourier transform (FFT) for PA imaging. A tungsten filament, asparagus fern leaf, and mouse auricle are imaged to demonstrate the method.
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