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Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice
Published on: May 10, 2019
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Aging process and central auditory pathway: a study based on auditory brainstem evoked potential and
Daniélli Rampelotto Tessele1, Bruna Pias Peixe1, Taissane Rodrigues Sanguebuche1
1Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
Einstein (Sao Paulo, Brazil)
|June 1, 2022
Summary
Elderly individuals exhibit slower neural responses in the auditory pathway, as shown by brainstem auditory evoked potential (BAEP) and frequency-following response (FFR) tests. This indicates reduced synchrony in auditory structures with aging.
Area of Science:
- Neuroscience
- Audiology
- Gerontology
Background:
- The central auditory pathway undergoes age-related changes.
- Understanding these changes is crucial for auditory health in the elderly.
Purpose of the Study:
- To analyze age-related alterations in the central auditory pathway of healthy older adults.
- To compare electrophysiological responses between young adults and elderly individuals.
Main Methods:
- Prospective, quantitative cross-sectional study.
- Involved 18 young adults and 18 elderly individuals.
- Utilized basic audiological evaluation, brainstem auditory evoked potential (BAEP), and frequency-following response (FFR).
Main Results:
- Elderly individuals showed significantly higher latencies in BAEP (waves I, III, V; interpeaks I-V, III-V).
- FFR latencies (waves A, E, F, O) were also elevated in the elderly.
- Reduced slope values and increased interpeak intervals (V-A, V-O) were observed in older adults.
Conclusions:
- BAEP and FFR are effective in assessing age-related auditory pathway changes.
- Slower neural responses in the elderly suggest decreased neural synchrony.
- These findings highlight functional auditory system changes associated with aging.
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