A Review on Green Synthesis of Silver Nanoparticles and its Role against Cancer
Neeraj Rani1, Rajeev K Singla2,3, Rakesh Redhu4
1Department of Pharmaceutical Sciences, Chaudhary Bansi Lal University, Bhiwani (HR), India.
Abstract:
Cancer is a fatal disease with a collection of related diseases in various body parts. The conventional therapies cannot show the desired results of treatment due to their imprecise targeting, deprived drug delivery, and side effects. Therefore, it is required to make the drug engineered so that it can target only cancerous cells and inhibit its growth and proliferation. Nanotechnology is a technology that can target and differentiate between cancerous cells and the body's normal cells. Silver itself is a good anticancer and antibacterial agent and employing it with phytochemicals with anticancer properties, and nanotechnology can give the best approach for the treatment. The synthesis of silver nanoparticles using plant extracts is an economical, energy-efficient, low-cost approach, and it doesn't need any hazardous chemicals. In the present review, we discussed different methods of synthesis of silver nanoparticles using herbal extracts and their role against cancer therapy along with the synergistic role of silver and plant extracts against cancer in the formulation.
Insights
This review explores using silver nanoparticles synthesized from plant extracts for cancer therapy. This eco-friendly nanotechnology offers targeted drug delivery, enhancing treatment efficacy against cancer.
Area of Science:
- Nanomedicine
- Oncology
- Green Chemistry
Background:
- Conventional cancer therapies face challenges like imprecise targeting, poor drug delivery, and significant side effects.
- There is a critical need for engineered drugs that selectively target cancer cells, inhibiting their growth and proliferation.
- Nanotechnology offers a promising approach to differentiate between cancerous and normal cells for targeted treatment.
Purpose of the Study:
- To review methods for synthesizing silver nanoparticles using plant extracts.
- To discuss the role of these silver nanoparticles in cancer therapy.
- To explore the synergistic effects of silver and plant extracts in cancer treatment formulations.
Main Methods:
- Synthesis of silver nanoparticles utilizing various plant extracts.
- Characterization of synthesized silver nanoparticles.
- Evaluation of anticancer and antibacterial properties of silver nanoparticles and plant extracts.
Main Results:
- Plant-mediated synthesis of silver nanoparticles is economical, energy-efficient, and avoids hazardous chemicals.
- Silver nanoparticles exhibit significant anticancer and antibacterial activities.
- Synergistic effects between silver nanoparticles and phytochemicals enhance anticancer efficacy.
Conclusions:
- Silver nanoparticles synthesized via green methods represent a viable and effective strategy for cancer therapy.
- This approach offers targeted drug delivery, improved efficacy, and reduced side effects compared to conventional treatments.
- Further research into synergistic formulations holds potential for advanced cancer treatment strategies.
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