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Updated: Sep 21, 2025

Author Spotlight: Development of a Minimally Invasive Large-Animal Model for Reliable and Reproducible Cardiovascular Research
Published on: October 20, 2023
Single Radial Access Simultaneous Left Ventricular and Ascending Aortic Pressure for the Evaluation of Aortic
Jaime Caballero, Cezar Iliescu, Mehmet Cilingiroglu
129333 Picana Lane, Wesley Chapel, FL 33543 USA. c.marmagiolis@gmail.com.
Insights
This study introduces a novel "double-barrel" technique using a single radial artery access for precise hemodynamic assessment of aortic stenosis. This method accurately evaluates patients with difficult echocardiograms, avoiding multiple or femoral access sites.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Medical Devices
Background:
- Accurate hemodynamic assessment is crucial for managing aortic stenosis, especially in equivocal echocardiogram cases.
- Cardiac catheterization with simultaneous pressure tracings is the gold standard for evaluating aortic stenosis severity.
- Current methods may involve multiple access sites or femoral access, posing potential risks and inconveniences.
Purpose of the Study:
- To describe the first-in-man application of a novel single radial access
- double-barrel
- technique for evaluating aortic stenosis.
- To demonstrate the feasibility and accuracy of this minimally invasive approach.
- To offer an alternative to traditional methods, potentially reducing complications and improving patient comfort.
Main Methods:
- A 7-Fr Glidesheath Slender hydrophilic-coated introducer sheath was placed in the right radial artery.
- Two 4-Fr pigtail catheters were advanced through the single sheath: one into the left ventricle and one into the ascending aorta.
- Simultaneous pressure tracings were obtained for hemodynamic assessment.
Main Results:
- The single radial access "double-barrel" technique was successfully implemented in a human subject.
- Accurate simultaneous left ventricular and ascending aortic pressure tracings were obtained.
- The procedure demonstrated the potential for precise hemodynamic evaluation of aortic stenosis severity.
Conclusions:
- The single radial access "double-barrel" technique is a simple and effective method for evaluating aortic stenosis.
- This technique provides accurate hemodynamic assessment, comparable to the gold standard.
- It offers a valuable alternative to multiple access sites or femoral access, potentially improving patient outcomes.
Abstract:
The use of simultaneous left ventricular and ascending aortic pressure tracings by cardiac catheterization is the gold standard of care for accurate hemodynamic assessment of aortic stenosis severity in patients with equivocal echocardiogram. We describe the first-in-man single radial access "double-barrel" technique for the evaluation of aortic stenosis. A 7-Fr Glidesheath Slender hydrophilic-coated introducer sheath (Terumo) was placed in the right radial artery. Two 4-Fr pigtails, 1 in the left ventricle and 1 in the ascending aorta, were advanced through the single sheath. The single radial access "double-barrel" technique is a simple way to accurately evaluate patients with aortic stenosis, avoiding multiple access sites or femoral access.
Related Concept Videos
Cardiac Catheterization II: Right Heart Catheterization
Assessment of apical radial pulse
The A-R pulse assessment involves simultaneous evaluation of the apical and radial pulses. When the apical and radial pulse rates vary, this assessment helps identify a pulse deficit.
Pre-Procedural Preparation
Assessment of blood pressure in brachial artery(two-step method)
Cardiac Catheterization III: Left Heart Catheterization
Sites for measruring blood pressure
The Brachial Artery: Primary Site for Blood Pressure Measurement

