Related Experiment Video
Updated: Sep 21, 2025

Light-Controlled Fermentations for Microbial Chemical and Protein Production
Published on: March 22, 2022
Lipophagy pathways in yeast are controlled by their distinct modes of induction
Garrett Fairman1,2, Mireille Ouimet1,2
1University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Abstract:
Lipid droplet (LD) autophagy (lipophagy) is a recently discovered selective form of autophagy and is a pathway for LD catabolism. This ubiquitous process has been an ongoing area of research within the budding yeast, Saccharomyces cerevisiae. Yeast lipophagy phenotypically resembles microautophagy, although it has a distinct set of genetic requirements depending on the mode of induction. This review highlights the similarities and differences between different forms of yeast lipophagy and offers perspectives on how our knowledge of lipophagy in yeast may guide our understanding of this process within mammalian cells to ultimately inform future applications of lipophagy.
Related Concept Videos
Yeast Signaling
Delivery Pathways to the Lysosome
Endocytosis
In endocytosis, the cell membrane takes up macromolecules and particles from the surrounding medium. Clathrin-mediated...
Inducible Operons: lac Operon
Gene Regulation During Sporulation
Export of Misfolded Proteins out of the ER

