Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Principles of Disease Surveillance01:26

Principles of Disease Surveillance

192
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
192
Introduction to Virus01:28

Introduction to Virus

271
Viruses are unique biological entities that blur the boundary between living and non-living systems. Although they lack cellular structure and metabolic processes, they can exhibit characteristics of life when infecting a host. Their defining feature is a nucleic acid core, composed of either DNA or RNA, encapsulated within a protein coat called a capsid. This simple structure allows them to invade host cells and use their machinery for replication efficiently.Viral Structure and...
271
Viruses with RNA Genomes01:29

Viruses with RNA Genomes

155
RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
155
Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

221
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
221
Viral Mutations00:36

Viral Mutations

33.4K
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
33.4K
Subviral Agents01:29

Subviral Agents

142
Subviral agents are infectious entities that resemble viruses but lack one or more viral components, such as a capsid or essential replication machinery. These agents include viroids, prions, and satellites, each possessing distinct structural and functional characteristics that influence their mode of infection and replication.Viroids are the simplest subviral agents, consisting of circular, single-stranded RNA molecules without a protein coat. They exclusively infect plants, relying entirely...
142

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Award honors pair for mRNA work key to COVID-19 vaccines.

Science (New York, N.Y.)·2023
Same author

Lurking in the deep freeze?

Science (New York, N.Y.)·2023
Same author

Gulls, floods, and superbugs.

Science (New York, N.Y.)·2023
Same author

Flight risks.

Science (New York, N.Y.)·2023
Same author

Polio eradication effort struggles with end game.

Science (New York, N.Y.)·2023
Same author

U.S. kills effort to hunt dangerous viruses.

Science (New York, N.Y.)·2023

Related Experiment Video

Updated: Sep 21, 2025

Remote Laboratory Management: Respiratory Virus Diagnostics
14:56

Remote Laboratory Management: Respiratory Virus Diagnostics

Published on: April 6, 2019

33.2K

Global outbreak puts spotlight on neglected virus.

Jon Cohen

    Science (New York, N.Y.)
    |June 2, 2022
    PubMed
    Summary
    This summary is machine-generated.

    Monkeypox cases in Africa have steadily increased, highlighting a growing public health concern. This situation demands urgent attention and research to understand and control the spread of the virus.

    More Related Videos

    Rescue and Characterization of Recombinant Virus from a New World Zika Virus Infectious Clone
    07:35

    Rescue and Characterization of Recombinant Virus from a New World Zika Virus Infectious Clone

    Published on: June 7, 2017

    9.8K
    Generation of Recombinant Arenavirus for Vaccine Development in FDA-Approved Vero Cells
    10:03

    Generation of Recombinant Arenavirus for Vaccine Development in FDA-Approved Vero Cells

    Published on: August 1, 2013

    17.1K

    Related Experiment Videos

    Last Updated: Sep 21, 2025

    Remote Laboratory Management: Respiratory Virus Diagnostics
    14:56

    Remote Laboratory Management: Respiratory Virus Diagnostics

    Published on: April 6, 2019

    33.2K
    Rescue and Characterization of Recombinant Virus from a New World Zika Virus Infectious Clone
    07:35

    Rescue and Characterization of Recombinant Virus from a New World Zika Virus Infectious Clone

    Published on: June 7, 2017

    9.8K
    Generation of Recombinant Arenavirus for Vaccine Development in FDA-Approved Vero Cells
    10:03

    Generation of Recombinant Arenavirus for Vaccine Development in FDA-Approved Vero Cells

    Published on: August 1, 2013

    17.1K

    Area of Science:

    • Epidemiology
    • Virology
    • Public Health

    Background:

    • The steady rise of monkeypox cases in Africa has historically received limited global attention.
    • Recent trends indicate a concerning increase in the incidence and geographical spread of monkeypox within the African continent.

    Discussion:

    • The underreporting and limited research on monkeypox in Africa may be contributing to a delayed response.
    • Understanding the epidemiological dynamics, transmission patterns, and viral evolution is crucial for effective control strategies.

    Key Insights:

    • Monkeypox virus (MPXV) poses a significant and growing threat in endemic regions.
    • Increased surveillance and diagnostic capacity are essential to accurately assess the burden of monkeypox.
    • The need for enhanced international cooperation and resource allocation for monkeypox research and control in Africa is evident.

    Outlook:

    • Further research is required to elucidate the factors driving the increased prevalence of monkeypox.
    • Strengthening public health infrastructure and implementing targeted interventions are critical for mitigating future outbreaks.
    • Global health organizations must prioritize monkeypox surveillance and response efforts in affected African nations.