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Updated: Sep 21, 2025

A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement
Published on: February 22, 2022
Constant-Load Exercise Versus High-Intensity Interval Training on Aerobic Fitness in Moderate-to-Severe Asthma: A
Ronaldo Aparecido da Silva1, Patrícia Gonçalves Leite Rocco1, Rafael Stelmach2
1Department of Physical Therapy, School of Medicine, University of São Paulo, São Paulo, Brazil.
High-intensity interval training (HIIT) improved aerobic fitness and reduced dyspnea in adults with asthma more than constant-load exercise. HIIT also enhanced asthma control and psychosocial well-being.
Area of Science:
- Exercise Physiology
- Respiratory Medicine
- Clinical Trials
Background:
- Effects of high-intensity interval training (HIIT) on asthma symptoms and aerobic capacity remain unclear.
- Understanding HIIT's impact on dyspnea and fitness in adults with moderate-to-severe asthma is crucial.
Purpose of the Study:
- To compare constant-load exercise (CLE) with HIIT for improving dyspnea and clinical control in adults with asthma.
- Evaluate the impact of different exercise intensities on asthma management and patient outcomes.
Main Methods:
- Randomized controlled trial with 12 weeks of twice-weekly cycle ergometer training.
- Participants assigned to either CLE (70% Wmax) or HIIT (80-140% Wmax) based on cardiopulmonary exercise testing.
- Assessed aerobic fitness, asthma control, quality of life, physical activity, anxiety, depression, and inflammation.
Main Results:
- Both CLE and HIIT improved aerobic fitness similarly.
- HIIT group demonstrated significantly lower dyspnea and fatigue, higher physical activity levels, and improved psychosocial distress.
- Only the HIIT group achieved clinically meaningful improvements in asthma symptoms.
Conclusions:
- Both exercise types enhance aerobic fitness in adults with asthma.
- HIIT offers superior benefits in reducing dyspnea, fatigue, and improving asthma control compared to CLE.
- HIIT represents a promising intervention for managing asthma symptoms and improving quality of life.
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