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Malignant Central Airway Obstruction: What's New?
Brian D Shaller1, Darius Filsoof1, Jorge M Pineda1
1Division of Pulmonary, Allergy and Critical Care Medicine, Stanford University School of Medicine, Stanford, California.
Seminars in Respiratory and Critical Care Medicine
|June 2, 2022
Summary
Malignant central airway obstruction (MCAO) management, though evolving slowly, offers interventional pulmonologists expanding endoscopic and non-endoscopic options for patient palliation. This review covers current and emerging MCAO treatments.
Area of Science:
- Pulmonology
- Oncology
- Interventional Medicine
Background:
- Malignant central airway obstruction (MCAO) is a severe complication in advanced intrathoracic cancer.
- Prompt palliation for MCAO increasingly relies on interventional pulmonologists.
- Therapeutic advancements in MCAO management have been slower compared to other interventional pulmonary fields.
Purpose of the Study:
- To review the current and emerging endoscopic and non-endoscopic management strategies for MCAO.
- To provide an overview of established and novel interventions for malignant obstructive lesions in the central airways.
Main Methods:
- Comprehensive review of existing literature on MCAO management.
- Discussion of both traditional and novel therapeutic approaches.
- Exploration of future directions in MCAO treatment.
Main Results:
- The spectrum of interventions for MCAO is expanding, albeit gradually.
- A range of endoscopic and non-endoscopic techniques are available for managing MCAO.
- Newer modalities are continuously being developed and integrated into clinical practice.
Conclusions:
- Interventional pulmonologists play a crucial role in managing MCAO.
- While progress has been incremental, the available interventions for MCAO continue to improve.
- The review highlights established, novel, and future therapeutic options for MCAO.
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