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Delayed Onset Nodules After Hyaluronic Acid Fillers: A Case Series
1A. K. Clinics, Ludhiana, Punjab, India.
Journal of Cutaneous and Aesthetic Surgery
|June 3, 2022
Summary
Delayed onset nodules, a rare side effect of hyaluronic acid fillers, can occur months after facial rejuvenation. Awareness of these granulomatous reactions is crucial for accurate diagnosis and treatment.
Area of Science:
- Dermatology
- Aesthetic Medicine
- Immunology
Background:
- Non-surgical facial rejuvenation using hyaluronic acid (HA) fillers is increasingly popular due to ease of use and rapid results.
- Despite a general safety profile, rare adverse events associated with HA fillers are being reported with greater frequency.
- The rising number of cosmetic procedures correlates with an increase in reported filler complications.
Observation:
- This case series details three patients who developed delayed onset nodules.
- These nodules appeared 1-5 months after receiving Juvederm Volift, a type of hyaluronic acid filler.
- The observed nodules are consistent with granulomatous reactions, which are localized immunological responses.
Findings:
- Delayed onset nodules can manifest several months post-injection of hyaluronic acid fillers.
- Juvederm Volift was implicated in all three presented cases of delayed nodules.
- Granulomatous reactions represent a potential, albeit rare, complication of hyaluronic acid filler treatments.
Implications:
- Increased physician and patient awareness of delayed adverse effects is essential.
- Prompt recognition aids in the accurate diagnosis of post-filler complications.
- Understanding these rare reactions improves patient management and treatment strategies for facial rejuvenation.
