Related Experiment Video

Updated: Sep 21, 2025

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects
05:46

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects

Published on: May 4, 2021

5.3K

Outcomes of HFNC Use in COVID-19 Patients in Non-ICU Settings: A Single-center Experience

Anivita Aggarwal1, Umang Arora1, Ankit Mittal1

  • 1Department of Medicine, All India Institute of Medical Sciences, New Delhi, India.

Indian Journal of Critical Care Medicine : Peer-Reviewed, Official Publication of Indian Society of Critical Care Medicine
|June 3, 2022
PubMed

Insights

High-flow nasal cannula (HFNC) oxygen therapy can be effective for COVID-19 patients outside the intensive care unit. This study shows favorable outcomes, suggesting HFNC is a viable treatment option in non-ICU settings.

Area of Science:

  • Critical Care Medicine
  • Respiratory Therapy
  • Infectious Diseases

Background:

  • The COVID-19 pandemic necessitated exploring effective oxygenation strategies.
  • Non-intensive care unit (non-ICU) settings require accessible and efficient respiratory support.
  • High-flow nasal cannula (HFNC) therapy is an alternative to conventional oxygen delivery.

Purpose of the Study:

  • To evaluate the outcomes of HFNC use in COVID-19 patients admitted to non-ICU wards.
  • To assess the safety and efficacy of HFNC in a real-world clinical setting.
  • To determine the impact of HFNC on patient recovery and resource utilization.

Main Methods:

  • A single-center retrospective study was conducted.
  • Patients with COVID-19 receiving HFNC in non-ICU settings were identified.
  • Outcomes such as oxygenation improvement, length of stay, and need for escalation were analyzed.

Main Results:

  • HFNC therapy demonstrated significant improvement in oxygenation levels.
  • A low rate of escalation to invasive mechanical ventilation was observed.
  • Patients treated with HFNC in non-ICU settings experienced favorable clinical outcomes.

Conclusions:

  • HFNC is a safe and effective modality for managing COVID-19 patients in non-ICU environments.
  • It can help optimize resource allocation by reducing ICU admissions.
  • Further research should explore optimal HFNC protocols in diverse patient populations.

Keywords:
COVID-19 ARDSHigh-flow Nasal Cannula (HFNC) oxygen therapyOutside-ICU

More Related Videos

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation04:46

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation

Published on: January 17, 2011

21.6K
An Educational Video Demonstration of How to Prone a Critically Ill Intubated Patient07:16

An Educational Video Demonstration of How to Prone a Critically Ill Intubated Patient

Published on: November 30, 2022

3.6K

Related Concept Videos

Administering Oxygen by Nasal Cannula01:29

Administering Oxygen by Nasal Cannula

Oxygen therapy is critical to patient care, especially for those struggling with respiratory issues. This intervention increases the oxygen concentration in the lungs, enhancing the amount of oxygen transported to the body's tissues. One standard method of delivering supplemental oxygen is through a nasal cannula, a non-invasive device that provides low to medium oxygen concentrations.
Nasal Cannulas
A nasal cannula is a lightweight tube split into two prongs placed in the nostrils,...
1.1K
Oxygen Delivering System I: Nasal Cannula and Face Mask01:26

Oxygen Delivering System I: Nasal Cannula and Face Mask

The human body requires oxygen to function, and when the natural process of respiration is hindered, external devices, including the following, are needed to help deliver this vital gas.
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
644
Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
249
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
389
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
341
Suctioning the Nasopharyngeal Airway01:29

Suctioning the Nasopharyngeal Airway

Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
1.0K