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Association of Accelerometer-Measured Sedentary Time and Physical Activity With Risk of Stroke Among US Adults
Steven P Hooker1, Keith M Diaz2, Steven N Blair3,4
1College of Health and Human Services, San Diego State University, San Diego, California.
JAMA Network Open
|June 3, 2022
Summary
Objectively measured sedentary time and physical activity levels are linked to stroke risk. Reducing sedentary time and increasing light-intensity physical activity (LIPA) or moderate- to vigorous-intensity physical activity (MVPA) may lower stroke risk.
Area of Science:
- Neurology
- Cardiovascular Health
- Public Health
Background:
- Previous stroke prevention research relied on self-reported physical activity, limiting accuracy.
- The independent risk of sedentary behavior for stroke remains unclear.
Purpose of the Study:
- To examine the association between accelerometer-measured sedentary time and physical activity (varying intensity and duration) and the risk of incident stroke.
Main Methods:
- A cohort study of 7607 US adults aged 45+ from the REGARDS study.
- Accelerometers measured sedentary time, light-intensity physical activity (LIPA), and moderate- to vigorous-intensity physical activity (MVPA) over 7 days.
- Incident stroke was the primary outcome, analyzed over a mean follow-up of 7.4 years.
Main Results:
- Higher sedentary time was associated with a 44% increased risk of stroke.
- Increased light-intensity physical activity (LIPA) and moderate- to vigorous-intensity physical activity (MVPA) were associated with lower stroke risk.
- Longer sedentary bout duration independently increased stroke risk.
Conclusions:
- Objectively measured sedentary time, LIPA, and MVPA are independently associated with incident stroke risk.
- Reducing sedentary time and increasing physical activity, even in short bouts, may be a beneficial stroke risk reduction strategy.
- The findings support the public health message to "move more and sit less" for stroke prevention.
