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Updated: Sep 21, 2025
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Published on: November 8, 2024
Time to Hemostasis After Trauma and Transfusion by Patient Blood Type
Justin L Miller1, Hallie Harper2, Hannah Jane McCarty3
1Justin L. Miller is a PhD student, School of Nursing, University of Alabama at Birmingham, NB 573G, 1720 2nd Ave S, Birmingham, AL 35294-1210 (jlmiller@uab.edu).
Background:
Although evidence supports an increased risk of mortality after major trauma among patients with type O blood, the relationship between patient blood type and clinical outcomes aside from mortality has not been fully elucidated.
Objective:
To examine the relationship between patient blood type and time to hemostasis after trauma and massive transfusion.
Methods:
A secondary analysis of the Pragmatic, Randomized Optimal Platelet and Plasma Ratios (PROPPR) trial was performed (N = 544). Blood type was dichotomized into type O versus non-type O. It was hypothesized that patients with non-type O blood would achieve hemostasis more quickly owing to the theoretical presence of increased clotting factors. Bivariate analysis and multiple Cox regression were conducted to test this assumption.
Results:
No significant difference was found in time to hemostasis between patients with type O blood and those with non-type O blood. However, mechanism of injury, diastolic blood pressure, and international normalized ratio affected the time to hemostasis in these trauma patients.
Conclusion:
This study showed no significant difference in time to hemostasis by blood type.
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