Related Experiment Video
Updated: Aug 17, 2026

Isolation of Human Atrial Myocytes for Simultaneous Measurements of Ca2+ Transients and Membrane Currents
Published on: July 3, 2013
Ethanol increases rate of isolated atria
Abstract:
Ethanol has a positive chronotropic and negative inotropic effect on isolated spontaneously beating rabbit atria. Both effects increased with increasing ethanol concentrations in the bathing medium. This response is apparently a direct action of ethanol on the myocardium and is not due to the release of catecholamines, acetylcholine, or acetaldehyde produced by the oxidative metabolism of ethanol. Ethanol is one of the few pharmacologic agents having opposite actions on heart rate and force of contraction.
Related Concept Videos
Mechanism of Cardiac Arrhythmias
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Dysrhythmias IV: Characteristics of Bradyarrhythmias

