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Updated: Jul 29, 2026

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Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice
Published on: May 10, 2019
Relationship between head size and latency of the auditory brainstem response
Summary
Larger head size in normally hearing individuals correlates with longer auditory brainstem response (ABR) latencies. This finding highlights head size as a key factor in ABR variability for clinical applications.
Area of Science:
- Neuroscience
- Audiology
- Biomedical Engineering
Background:
- Auditory brainstem response (ABR) is a key diagnostic tool.
- Understanding factors influencing ABR latency is crucial for accurate interpretation.
- Head size variability is a potential confounder in ABR measurements.
Purpose of the Study:
- To investigate the correlation between head size and auditory brainstem response (ABR) latency in normally hearing adults.
- To determine if head size influences specific ABR waveform latencies.
Main Methods:
- Examined 22 normally hearing adults (12 female, 10 male) with diverse head sizes.
- Measured absolute latency of Wave V and the I-V interpeak interval.
- Analyzed correlations between head size and measured ABR latencies.
Main Results:
- A significant positive correlation was found between head size and Wave V latency.
- A strong positive correlation was observed between head size and the I-V interpeak interval.
- Results indicate that larger head size is associated with longer ABR latencies.
Conclusions:
- Head size is a significant factor contributing to intersubject variability in ABR.
- Differences in brain size, reflected by head size, likely underlie the observed latency correlations.
- Considering head size in ABR analysis can enhance its clinical utility and diagnostic accuracy.

