Related Experiment Video
Updated: Sep 20, 2025

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
Published on: January 12, 2018
Use of Race in Pediatric Clinical Practice Guidelines: A Systematic Review
Courtney A Gilliam1, Edwin G Lindo2, Shannon Cannon3
1Division of Hospital Medicine, Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle.
Insights
Pediatric clinical practice guidelines (CPGs) often use race in ways that may worsen health inequities. Medical organizations can improve CPGs to ensure race is used to promote health equity for all children.
Area of Science:
- Health Equity Research
- Clinical Practice Guidelines
- Pediatric Health
Background:
- National clinical practice guidelines (CPGs) shape medical practice.
- The inclusion of race in CPGs can impact structural racism and health inequities, both positively and negatively.
Purpose of the Study:
- To systematically review the utilization of race within published pediatric CPGs.
- To assess the potential impact of race usage on structural racism and health disparities in pediatric care.
Main Methods:
- A comprehensive literature search was conducted across multiple databases (PubMed, Medscape, ECRI, MetaLib.gov) for pediatric CPGs published between January 1, 2016, and April 30, 2021.
- A critical race theory framework was employed to classify the identified uses of race and ethnicity terms based on their potential to affect health inequities.
Main Results:
- Out of 414 identified pediatric CPGs, 126 (30%) incorporated race or ethnicity terms.
- Race was mentioned 175 times within CPGs. Of these, 87 instances (49.7%) had a potential negative effect on health inequities, while 50 instances (28.6%) had a potential positive effect.
Conclusions:
- The review of US-based pediatric CPGs indicates frequent use of race in ways that may exacerbate health care inequities.
- National medical organizations have significant opportunities to refine the application of race in CPGs to advance health equity, especially for racial and ethnic minority children.
Importance:
National clinical practice guidelines (CPGs) guide medical practice. The use of race in CPGs has the potential to positively or negatively affect structural racism and health inequities.
Objective:
To review the use of race in published pediatric CPGs.
Evidence Review:
A literature search of PubMed, Medscape, Emergency Care Research Institute Guidelines Trust, and MetaLib.gov was performed for English-language clinical guidelines addressing patients younger than 19 years of age from January 1, 2016, to April 30, 2021. The study team systematically identified and evaluated all articles that used race and ethnicity terms and then used a critical race theory framework to classify each use according to the potential to either positively or negatively affect structural racism and racial inequities in health care.
Findings:
Of 414 identified pediatric clinical practice guidelines, 126 (30%) met criteria for full review because of the use of race or ethnicity terms and 288 (70%) did not use race or ethnicity terms. The use of a race term occurred 175 times in either background, clinical recommendations, or future directions. A use of race with a potential negative effect occurred 87 times (49.7%) across 73 CPGs and a positive effect 50 times (28.6%) across 45 CPGs.
Conclusions And Relevance:
In this systematic review of US-based pediatric CPGs, race was frequently used in ways that could negatively affect health care inequities. Many opportunities exist for national medical organizations to improve the use of race in CPGs to positively affect health care, particularly for racial and ethnic minoritized communities.
Related Concept Videos
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Standards of Care II
Bias in Epidemiological Studies
Standards of Care I
Clinical Trials: Overview
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...

