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Research in Pediatric Intensive Care

Andrew Prout1, Kathleen L Meert2

  • 1Division of Pediatric Critical Care Medicine, Discipline of Pediatrics, Children's Hospital of Michigan, Floor Carls Building, 3901 Beaubien Boulevard, Detroit, MI, 48201, USA; Central Michigan University, Mt. Pleasant, MI, USA.

Pediatric Clinics of North America
|June 6, 2022
PubMed

Insights

Conducting high-quality research in pediatric intensive care units (PICUs) is crucial for advancing clinical practice. This review highlights key strategies like research agendas, core outcomes, and innovative trials to address evidence gaps in pediatric intensive care.

Area of Science:

  • Pediatric Intensive Care Medicine
  • Clinical Research Methodology
  • Evidence-Based Practice

Background:

  • Significant clinical questions in pediatric intensive care lack high-quality evidence.
  • Conducting research in pediatric intensive care units (PICUs) presents unique challenges.

Purpose of the Study:

  • To review key themes and strategies for advancing research in PICUs.
  • To address the broad topic of "Research in PICUs" by focusing on current attention areas.

Main Methods:

  • Literature review focusing on common themes in PICU research.
  • Identification of strategies to overcome research challenges.

Main Results:

  • Key themes include research agendas, core outcome sets, precision medicine, and novel clinical trial strategies.
  • Interdisciplinary collaboration and common datasets are vital for generating new knowledge.

Conclusions:

  • Addressing evidence gaps in pediatric intensive care requires strategic research approaches.
  • Innovative trial designs and standardized outcomes are essential for progress in PICU research.

Keywords:
ChildrenClinical trialsCore outcome setsInfantsPediatric intensive care unitPrecision medicineResearch agenda

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