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Optical Control of Living Cells Electrical Activity by Conjugated Polymers

Optical Control of Living Cells Electrical Activity by Conjugated Polymers

Published on: January 28, 2016

Stimuli-Responsive Polymers for Biological Detection and Delivery.

Theresa M Reineke¹

¹Department of Chemistry, University of Minnesota, 207 Pleasant Street SE, Minneapolis, Minnesota 55455-0431, United States.

ACS Macro Letters

|June 7, 2022

Summary

Smart responsive polymers are revolutionizing biomaterials with tailored properties for applications in diagnostics, imaging, and drug delivery. These advanced materials offer precise control over degradation and release, enhancing therapeutic efficacy and safety.

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Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors

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Published on: September 10, 2013

Area of Science:

Polymer Chemistry
Biomaterials Science
Chemical Engineering

Background:

Responsive polymers offer tunable properties for advanced biomaterial applications.
Current innovations focus on creating "smart" materials that interact with their environment.
Applications span diagnostics, imaging, tissue engineering, and drug delivery.

Purpose of the Study:

To highlight innovative chemical attributes of responsive polymers.
To showcase advancements in "smart" biomaterial design.
To explore the potential of tailored polymer properties in various biomedical fields.

Main Methods:

Review of research articles in ACS Macro Letters focusing on responsive polymers.
Analysis of chemical attributes including pH-triggered degradation, reduction-based release, and photomodulation.
Examination of properties like glucose responsiveness, thermal sensitivity, and membrane permeating peptides.

Main Results:

Demonstration of diverse responsive polymer functionalities (pH, redox, light, glucose, thermal).
Highlighting the incorporation of membrane-permeating peptides for enhanced delivery.
Showcasing the custom tailoring of polymer properties for specific applications.

Conclusions:

Responsive polymers enable "smart" design features for custom biomaterials.
Tailored polymer properties enhance biological delivery, pharmaceutical potency, and disease diagnosis.
These advancements are crucial for innovative solutions in medicine and biotechnology.