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Three-Dimensional Echocardiography and Coagulation Function Detection in the Prognosis Evaluation of Patients with
Yatong Zhang1, Zinan Zhao1, Li Zheng2
1Department of Pharmacy, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Key Laboratory of Assessment of Clinical Drugs Risk and Individual Application (Beijing Hospital), Beijing 100730, China.
Insights
This study found that three-dimensional echocardiography and coagulation function tests can effectively evaluate the prognosis of acute myocardial infarction (AMI) patients. Lower levels of coagulation factors and specific echocardiographic parameters indicate better recovery in AMI patients.
Area of Science:
- Cardiology
- Medical Imaging
- Biochemistry
Background:
- Acute myocardial infarction (AMI) poses significant challenges in prognosis evaluation.
- Accurate assessment of recovery is crucial for patient management and treatment strategies.
Purpose of the Study:
- To investigate the application value of coagulation function detection and three-dimensional echocardiography in evaluating the prognosis of AMI patients.
- To identify key indicators from these methods that correlate with patient recovery outcomes.
Main Methods:
- Seventy-two AMI patients were divided into recovered and unrecovered groups based on postoperative ultrasonography.
- Three-dimensional echocardiography was used to assess left ventricular parameters.
- Coagulation function tests were performed on all patients.
Main Results:
- Left ventricular regional volumes decreased and regional ejection fraction increased significantly in patients 3 months post-surgery compared to 1 week post-surgery (P < 0.05).
- Three-dimensional echocardiography provided significantly different measurements for end-systolic volume, end-diastolic volume, and ejection fraction compared to two-dimensional ultrasound (P < 0.05).
- Specific parameters (Tmsvle6-Dif% and Tmsvl6-SD%) and coagulation factor levels were significantly lower in the recovered group compared to the unrecovered group (P < 0.05).
Conclusions:
- Three-dimensional echocardiography is valuable for assessing cardiac conditions in AMI patients.
- Coagulation factor levels correlate with AMI patient outcomes, offering a reference for prognosis evaluation.
- Combined use of advanced echocardiography and coagulation tests enhances prognostic accuracy for AMI.
Abstract:
This research was aimed at discussing the application value of coagulation function detection and three-dimensional echocardiography in the prognosis evaluation of acute myocardial infarction (AMI) patients. 72 patients with AMI were divided into the recovered group (good recovery) and unrecovered group (poor recovery) according to the results of postoperative ultrasonography. The left ventricular parameters of the patients were detected by three-dimensional ultrasound, and the coagulation function was also detected. The results showed that 3 months after surgery, the regional end-systolic volume (rESV) and regional end-diastolic volume (rEDV) of the left ventricle in the patients were smaller than the measured values 1 week after surgery. The left ventricular regional ejection fraction (rEF) was greater than the value measured 1 week after surgery, and all the differences were statistically significant (P < 0.05). For the end-systolic volume (ESV), end-diastolic volume (EDV), and ejection fraction (EF) (%), the two-dimensional ultrasound results were significantly lower than the three-dimensional ultrasound results, and there were significant differences (P < 0.05). Tmsvle6-Dif% of the recovered patients was 14.99 ± 9.88 and 14.37 ± 9.78 3 months and 6 months after surgery, respectively. These were smaller than 30.91 ± 18.63 and 33.51 ± 17.96 of the unrecovered patients; the differences were of statistical significance (P < 0.05). Tmsvl6-SD% of recovered patients was 3.69 ± 2.47 and 3.61 ± 1.83 3 months and 6 months after surgery, respectively, which were also smaller than 7.38 ± 4.06 and 7.96 ± 2.82 of unrecovered patients, showing statistically significant difference (P < 0.05). The postoperative Tmsvle6-Dif% and Tmsvl6-SD% of the recovered group were lower than those of the unrecovered patients, with the statistically significant differences (P < 0.05). The level of coagulation factors in the recovered group was also significantly lower than that in the unrecovered group with the difference statistically significant (P < 0.05). The results suggested that three-dimensional echocardiography played an important role in the evaluation of cardiac conditions in AMI patients. The level of coagulation factors varied with the AMI condition of patients, and there was an obvious relationship between them, which could provide a reference value for the prognosis evaluation of patients.
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