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Interconnected Clinical and Social Risk Factors in Breast Cancer and Heart Failure
Arjun Sinha1, Avni Bavishi2, Elizabeth A Hibler3
1Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Insights
Preventing breast cancer and heart failure requires addressing both clinical risks and social determinants of health. A comprehensive approach integrates lifestyle factors for better chronic disease prevention.
Area of Science:
- Cardiovascular Health
- Oncology
- Public Health
Background:
- Breast cancer and heart failure share clinical risk factors like obesity, hypertension, and inflammation.
- Understanding the interplay requires exploring biological and social determinants of health.
Purpose of the Study:
- To review clinical and social determinants of health impacting breast cancer and heart failure risk.
- To inform effective prevention strategies for both chronic diseases.
Main Methods:
- Literature review examining clinical risk factors.
- Analysis of social determinants of health (SDOH) impacting prevention and treatment.
- Synthesis of findings for a comprehensive prevention approach.
Main Results:
- Shared clinical risk factors necessitate integrated management.
- Social determinants like socioeconomic status and healthcare access significantly impede prevention efforts.
- Addressing root causes of modifiable risk factors is crucial.
Conclusions:
- Effective prevention of breast cancer and heart failure demands assessment of both clinical and social factors.
- A comprehensive strategy integrating SDOH is essential for reducing the risk of these chronic diseases.
Abstract:
Breast cancer and heart failure share several known clinical cardiovascular risk factors, including age, obesity, glucose dysregulation, cholesterol dysregulation, hypertension, atrial fibrillation and inflammation. However, to fully comprehend the complex interplay between risk of breast cancer and heart failure, factors attributed to both biological and social determinants of health must be explored in risk-assessment. There are several social factors that impede implementation of prevention strategies and treatment for breast cancer and heart failure prevention, including socioeconomic status, neighborhood disadvantage, food insecurity, access to healthcare, and social isolation. A comprehensive approach to prevention of both breast cancer and heart failure must include assessment for both traditional clinical risk factors and social determinants of health in patients to address root causes of lifestyle and modifiable risk factors. In this review, we examine clinical and social determinants of health in breast cancer and heart failure that are necessary to consider in the design and implementation of effective prevention strategies that altogether reduce the risk of both chronic diseases.
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