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Updated: Sep 20, 2025

Dissection of Human Retina and RPE-Choroid for Proteomic Analysis

Dissection of Human Retina and RPE-Choroid for Proteomic Analysis

Published on: November 12, 2017

Mass spectrometry-based retina proteomics.

Laszlo Prokai¹, Khadiza Zaman¹, Katalin Prokai-Tatrai¹

¹Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, Texas, USA.

Mass Spectrometry Reviews

|June 7, 2022

Summary

Retina proteomics, a neuroproteomics subfield, has advanced significantly. Mass spectrometry is key for cataloging retinal proteins, their modifications, and understanding eye health and disease.

Keywords:

biomarkers estrogenic retina photobiology posttranslational modifications protein expression proteomics retina retinal diseases therapeutic targets

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Published on: February 22, 2019

Area of Science:

Neuroproteomics
Retina proteomics
Mass spectrometry

Background:

Retina proteomics has grown due to advances in chemical, biochemical, and molecular biology.
Understanding the retina's proteome is crucial for biology, health, and disease research.

Purpose of the Study:

To review the contributions of mass spectrometry to retina proteomics.
To highlight applications in cataloging and quantifying retinal proteins and their modifications.

Main Methods:

Focus on mass spectrometry techniques.
Review of studies on mammalian and avian retina proteomics.

Main Results:

Mass spectrometry enables cataloging and quantification of retinal proteins.
Mass spectrometry aids in determining posttranslational modifications of retinal proteins.

Conclusions:

Mass spectrometry is a vital tool for retina proteomics research.
Applications extend to understanding retinal biology, diseases, and therapeutic developments.