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Updated: Sep 20, 2025

Inducing Apical Periodontitis in Mice
Published on: August 6, 2019
[A periapical lesion, not always an inflammation. Periapical radiolucencies]
Abstract:
A radiolucency, radiopacity or mixed lesion, identified on a radiograph is usually the result of an inflammation of endodontic origin. However, a periapical lesion is sometimes caused by primary bone pathology, predominantly manifesting at the apices of the teeth. Various intraosseous lesions can be projected across the apices, creating the impression of a causal relation with these teeth. An incorrect diagnosis can lead to 1 or more endodontic treatments being carried out unjustifiably. A thorough and detailed anamnesis, a complete extra- and intraoral examination, and a careful examination of the radiological imaging will result in a correct diagnosis in most cases. Knowledge of the differential diagnosis of periapical lesions is essential. In this article, the focus will be on periapical radiolucencies and how they can be distinguished from each other.
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