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1,5-Allyl Shift by a Sequential Achmatowicz/Oxonia-Cope/Retro-Achmatowicz Rearrangement

Xiayan Zhang1,2, Yi Tong1, Gang Li3

  • 1Department of Chemistry, The Hong Kong University of Science and Technology, Clearwater Bay, Kowloon, Hong Kong, China.

Angewandte Chemie (International Ed. in English)
|June 7, 2022
PubMed
Summary

Researchers discovered a new 2-step method for a 1,5-allyl shift, overcoming a forbidden rearrangement. This novel organic synthesis technique involves sequential ring expansion and contraction, expanding possibilities in chemistry.

Keywords:
CyclizationsHeterocyclesReaction MechanismsRearrangementsSynthetic Methods

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