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Updated: Jul 27, 2026

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Flat Mount Imaging of Mouse Skin and Its Application to the Analysis of Hair Follicle Patterning and Sensory Axon Morphology
Published on: June 25, 2014
A family with diffuse partial woolly hair.
The British Journal of Dermatology
|March 1, 1987
Summary
A family presented with a rare scalp hair abnormality, featuring shorter, finer, kinky hairs mixed with normal hair. This condition caused noticeable hair thinning in two affected individuals.
Area of Science:
- Dermatology
- Genetics
- Trichology
Background:
- The study investigates a rare inherited hair shaft abnormality.
- Focuses on the clinical presentation and familial occurrence of specific hair morphology.
Observation:
- A family of six individuals exhibited an unusual scalp hair phenotype.
- Characterized by a mixture of normal hairs and shorter, finer, kinky hairs distributed across the scalp.
Findings:
- The hair abnormality was subclinical in four family members.
- Two individuals reported subjective scalp hair thinning, suggesting a potential link between the hair morphology and perceived hair density.
Implications:
- This finding contributes to the understanding of hair shaft disorders.
- Highlights the importance of detailed clinical examination for diagnosing subtle hair abnormalities.
- Suggests potential genetic factors influencing hair texture and density within families.
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