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Posttraumatic pulmonary microembolism. Pathophysiology and treatment.

J Modig

    Annals of Clinical Research
    |June 1, 1977
    PubMed
    Summary

    Posttraumatic pulmonary microembolism, a cause of respiratory insufficiency, arises from injured tissues releasing microemboli. Early intervention with ventilation and medication is crucial for treatment.

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    Area of Science:

    • Pulmonary Medicine
    • Trauma Surgery
    • Critical Care Medicine

    Background:

    • Respiratory insufficiency can follow trauma, surgery, or illness.
    • The pathogenesis of a specific syndrome remains controversial.
    • This review focuses on posttraumatic pulmonary microembolism.

    Purpose of the Study:

    • To review the concept and pathogenesis of posttraumatic pulmonary microembolism.
    • To outline preventive strategies.
    • To describe treatment protocols for impending respiratory dysfunction.

    Main Methods:

    • Clinical investigations
    • Pathologico-anatomical studies
    • Experimental studies

    Main Results:

    • Posttraumatic pulmonary microembolism is characterized by platelet and fibrin microemboli trapped in the lungs.
    • The mechanism involves thromboplastic products from injured tissues and inhibited fibrinolysis.
    • Preventive measures include hemodynamic support and fracture stabilization.
    • Treatment involves early mechanical ventilation with PEEP, heparin, and corticosteroids.

    Conclusions:

    • Posttraumatic pulmonary microembolism is a significant cause of respiratory insufficiency.
    • Prompt diagnosis and management are essential.
    • Multifaceted treatment strategies improve outcomes.

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