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Updated: Sep 20, 2025

Intravascular Delivery of Biologics to the Rat Kidney
Published on: September 1, 2016
IgA vasculitis with severe renal manifestation
Joana Marques Dias1, Marta Azevedo Ferreira2, Ana Grilo2
1Internal Medicine, Hospital Beatriz Angelo, Loures, Lisboa, Portugal joana.marques.dias92@gmail.com.
Abstract:
IgA vasculitis is a rare systemic vasculitis in adults, frequently more severe than in paediatric age. It manifests with cutaneous, articular, gastrointestinal and renal involvement.We present a case of a man in his 40s diagnosed with IgA vasculitis with cutaneous, joint, gastrointestinal and renal disease. Significant proteinuria and renal biopsy findings demonstrating crescentic glomerulonephritis led to the onset of early immunosuppression with corticoid and cyclophosphamide. This case report reflects a case of more severe renal impairment due to IgA vasculitis with good outcome with the chosen therapy. The findings in the renal biopsy after treatment supported the good response to the chosen immunosuppression.
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