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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Updated: Sep 20, 2025

Whole Body Vibration Methods with Survivors of Polio
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Published on: October 17, 2018

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Describing post-polio syndrome.

M P Sáinz1, R Pelayo1, S Laxe2

  • 1Brain Injury Unit of Fundación Institut Guttmann, Institut Universitary de Neurorehabilició adscrit a la UAB, Barcelona, Spain.

Neurologia
|June 7, 2022
PubMed
Summary
This summary is machine-generated.

Post-polio syndrome (PPS) affects women more frequently, with pain and fatigue being common symptoms. Objective measures are crucial for diagnosing PPS due to diverse clinical presentations.

Keywords:
PoliomielitisPoliomyelitisPoliomyelitis sequelaePost-polio syndromeSecuelas de polioSíndrome pospolio

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Area of Science:

  • Neurology
  • Epidemiology
  • Clinical Medicine

Background:

  • Post-polio syndrome (PPS) is characterized by new or worsening symptoms in individuals with a history of poliomyelitis.
  • Understanding the clinical and epidemiological profile of PPS is essential for accurate diagnosis and management.

Purpose of the Study:

  • To identify the clinical, functional, and epidemiological characteristics of patients with post-polio syndrome (PPS).
  • To analyze the relationship between poliomyelitis onset, disease severity, sex, and PPS symptom frequency.

Main Methods:

  • Retrospective study of 400 poliomyelitis patients, with 310 diagnosed with PPS.
  • Collection and analysis of epidemiological, clinical, and electromyographic data.
  • Investigation of correlations between age at poliomyelitis onset, disease severity, sex, and PPS symptom presentation.

Main Results:

  • PPS diagnosed in 310 patients, more prevalent in women (57.7%). Mean age at onset 52.4 years.
  • Common symptoms include pain (85%), fatigue (65.5%), tiredness (57.8%), and depression (31.5%).
  • Fatigue, tiredness, depression, and cognitive issues were more frequent in women. Electromyographic findings suggestive of PPS were present in 59%.

Conclusions:

  • Observed symptom frequencies in PPS differ from existing literature, highlighting diverse patient profiles.
  • Emphasis on objective parameters like symptom worsening or weakness is recommended for diagnosis.
  • Further research involving biomarker analysis may improve diagnostic accuracy for post-polio syndrome.