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Related Experiment Video

Updated: Sep 20, 2025

Laparoscopic Repair of Para-Esophageal Hernia Using Absorbable Biosynthetic Mesh
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Prolonged Emesis Causing Esophageal Perforation: A Case Report.

Nandita Kakar1, Harrison C Smith1, Anthony M Shadid2

  • 1Medicine, Nova Southeastern University Dr. Kiran C. Patel College Of Osteopathic Medicine, Fort Lauderdale, USA.

Cureus
|June 8, 2022
PubMed
Summary

Boerhaave syndrome, a severe esophageal rupture, has high mortality due to delayed diagnosis. Prompt treatment within 24 hours, including surgical repair and drainage, significantly improves survival rates.

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Area of Science:

  • Gastroenterology
  • Thoracic Surgery
  • Emergency Medicine

Background:

  • Transmural esophageal rupture, or Boerhaave syndrome, presents significant diagnostic and management challenges.
  • Patient heterogeneity in age, comorbidities, and illness severity complicates clinical decision-making.
  • Distal esophageal rupture can lead to mediastinal necrosis and bacterial infection from gastric content leakage.

Observation:

  • Delayed diagnosis and treatment are primary contributors to the high mortality associated with Boerhaave syndrome.
  • Symptoms are often heterogeneous, making early recognition difficult.
  • The condition involves leakage of gastric contents into the thoracic cavity, causing severe complications.

Findings:

  • Prompt detection and intervention, including conservative care and/or surgical repair, are crucial for managing Boerhaave syndrome.
Keywords:
boerhaave syndromecrepitusemesisesophageal perforationsubcutaneous emphysema

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  • Early recognition within 24 hours is critical for optimal outcomes.
  • Primary esophageal repair combined with mediastinal and chest drainage within 24 hours is linked to a 90% survival rate.
  • Implications:

    • Emphasizes the critical need for rapid diagnosis and intervention in esophageal rupture cases.
    • Highlights the importance of timely surgical repair and drainage for improving patient survival.
    • Suggests that adherence to a strict treatment timeline can dramatically reduce mortality in Boerhaave syndrome.